IACH News of the week
IACH News of the Week, curated by Dr Edwin Uriel Suárez , is a weekly summary of the latest advancements and discoveries in the field of hematology compiled in an easy-to-digest format. It highlights research breakthroughs, clinical trial results, interesting case studies, and important health advisories – all within the last week. This is a valuable tool for medical professionals with limited time to stay up-to-date on the ever-evolving world of hematology.
- EZH2 mutation status predicts inferior outcomes after bendamustine‐based immunochemotherapy in frontline follicular lymphoma: A GELTAMO multicenter validation study (Letter; Retrospective multicenter cohort)
- Frontline Bruton tyrosine kinase inhibitors are associated with improved response and PFS in primary CNS lymphoma (Retrospective study)
- How I treat autoimmune neutropenia in adults (Review)
- Emerging novel therapies for the treatment of hereditary haemorrhagic telangiectasia (Review)
- New Drugs in Myelofibrosis: Incremental Progress in Symptom Management Without Disease Modification (Review)
- Newly diagnosed and relapsed follicular lymphoma: EHA Clinical Practice Guidelines for diagnosis, treatment, and follow‐up
- American Society of Hematology 2026 Guidelines for the Management of Myelofibrosis in Adults
- How I Identify and Diagnose Carriers of Hemophilia and Women and Girls with Hemophilia (Review)
- Molecular surveillance of aggressive large B-cell lymphoma using circulating tumor DNA duplexes (Secondary analysis of a prospective phase II clinical trial cohort)
- ASCT Consensus Grading for Toxicities after Immune Effector Cell Therapy (Guidelines).
- Hematopoietic Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm: Clinical Practice Guidelines From the American Society for Transplantation and Cellular Therapy (Guidelines).
- Minor histocompatibility antigen TCR-T (Review)
- How I Treat: MRD testing to personalize allogeneic HCT for adults with AML (Review).
- iMTSS: An Integrated Framework for Biology- and Patient-Driven Prognosis in Myelofibrosis Undergoing Transplantation (Retrospective cohort).
- Reduced-Dose Post-Transplant Cyclophosphamide (PTCy 40-40) in Allogeneic Hematopoietic Cell Transplantation
- Early Graft-Versus-Host Disease Prophylaxis to Prevent Cytokine Release Syndrome after Haploidentical Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis (Systematic review and meta-analysis)
- Topical ruxolitinib for chronic cutaneous graft-versus-host disease: a single-centre, randomised, double-blind, intra-patient-controlled phase 2 trial
- BEAM versus EAM, FEAM, BeEAM, and TEAM: exploring conditioning strategies in autologous stem cell transplantation for Hodgkin lymphoma a retrospective study of the LWP of EBMT (Registry-based, multicenter study)
- Diagnosis and Management of Chronic Lymphocytic Leukemia with TP53 Loss of Function in the Novel Agent Era (Review)
- Inherited microcytic anemias due to disorders of iron and heme metabolism: An updated clinical review
- At the heart of unmet need: TP53 myeloid neoplasms (Review)
- CAR T cells for autoimmune diseases: 2026 update of the EBMT–ISCT–JACIE practice harmonisation and consensus recommendations (Review)
- How I treat thrombotic microangiopathy in the setting of triggers (Review)
- Efficacy and safety of tirabrutinib monotherapy for relapsed/refractory primary CNS lymphoma: PROSPECT phase 2 trial
- Relapsed Hodgkin lymphoma: should all patients receive an autologous stem cell transplant? (PRO and CON Editorial from Haematologica Journal)
- Clinicopathological characteristics and therapeutic outcomes of Kimura disease: A real-world study (Research letter)
- Phase 1 Study of Anito-cel, a D-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma
- Incidentally detected vertebral fractures and risk of myeloma: a prospective cohort study of 9059 CT-scanned Danish general population individuals (Letter)
- How I Treat: MRD testing to personalize allogeneic HCT for adults with AML (Review)
- Venetoclax plus Inotuzumab Ozogamicin for Relapsed and Refractory Acute Lymphoblastic Leukemia (Phase 1 Clinical Trial)
- A practical approach to risk stratification of incidental T-cell clonality (Review)
- IFM 2026 Recommendations for First-Line Treatment of Newly Diagnosed Multiple Myeloma
- High time for risk-adapted treatment in mantle cell lymphoma (Review)
- High-dose chemotherapy followed by autologous stem-cell transplantation versus non-myeloablative consolidation in primary CNS lymphoma (MATRix/IELSG43): a randomised phase 3 trial
- Blinatumomab for Replacing Chemotherapy in Pediatric Acute Lymphoblastic Leukemia (Phase 3 Clinical Trial)
- Myelodysplasia in VEXAS syndrome (Review)
- American Society of Hematology 2026 guidelines for the diagnosis and management of severe and very severe acquired aplastic anemia
- How I Treat Pediatric Hematology-Oncology Patients from Families Identifying as Jehovah’s Witnesses (Review)
- Outbreak of Severe Methemoglobinemia during Maritime Migration (Descriptive case series)
- Diagnostic Accuracy of Fat Pad Sampling and Bone Marrow Biopsy for AL Amyloidosis: A Systematic Review and Meta-Analysis
- Low-dose ruxolitinib for graft-versus-host disease prevention in haploidentical haematopoietic stem-cell transplantation: a multicentre, open-label, randomised, controlled, phase 3 trial
- Abnormal serum immunofixation patterns are common after BCMA CAR-T in multiple myeloma and are preceded by immune events (Retrospective study)
- Arlocabtagene autoleucel: a GPRC5D-targeted CAR T-cell therapy for heavily pretreated relapsed/refractory multiple myeloma (Phase 1 clinical trial)
- Frequency, kinetics, and clinical significance of HHV-6 DNAemia after PTCy-based hematopoietic cell transplant (Prospective cohort study)
- Consolidation Therapy with Checkpoint Inhibitors After Autologous Hematopoietic Cell Transplantation in Patients with High-Risk Multiple Myeloma and Lymphoma (Prospective study)
- PTCy-based allo-BMT platform as a curative, accessible alternative for pediatric and young adult severe aplastic anemia (Retrospective cohort)
- TA-TMA and GVHD are distinct consequences of endothelial injury: a MIDAS consortium study [Prospective cohort]
- Older Age, STAG2, and DNMT3A Mutations Predict Superior Posttransplant Survival in Newly Diagnosed Acute Myeloid Leukemia Treated With Venetoclax Plus Hypomethylating Agents (Retrospective cohort)
- Mitigating HLA Disparity in AML Transplantation: Comparable Outcomes After Haploidentical and 9/10 Mismatched Unrelated Donor Transplantation With Treosulfan and PTCy (Retrospective cohort)
- Outcomes After Matched Sibling Donor Versus Haploidentical Hematopoietic Stem Cell Transplantation With Post-Transplant Cyclophosphamide-Based GVHD Prophylaxis (Retrospective cohort)
- Azacitidine–Venetoclax or Induction Chemotherapy for Acute Myeloid Leukemia (Phase 2 clinical trial)
- Early treatment with rasburicase and risk of kidney replacement therapy and death in adults with tumour lysis syndrome: emulated target trial
- A framework to challenge the dogma of incurability in follicular lymphoma (Review)
- Technical Considerations in the choice and use of ctDNA for Large B-cell lymphoma (LBCL) (Review)
- New Paradigms in the Management of Castleman Disease (Review)
Looking for earlier issues? Visit the News of the Week Archive.