IACH News of the week
IACH News of the Week, curated by Dr Edwin Uriel Suárez , is a weekly summary of the latest advancements and discoveries in the field of hematology compiled in an easy-to-digest format. It highlights research breakthroughs, clinical trial results, interesting case studies, and important health advisories – all within the last week. This is a valuable tool for medical professionals with limited time to stay up-to-date on the ever-evolving world of hematology.
News of the Week– May 8, 2025 (CLICK TO VIEW)
- Revised free light chain reference intervals enhance risk stratification in monoclonal gammopathy of undetermined significance and reduce overdiagnosis [Retrospective cohort].
- Molecular monitoring versus standard clinical care in younger adults with acute myeloid leukaemia: results from the UK NCRI AML17 and AML19 randomised, controlled, phase 3 trials.
- Updated recommendations for the management of hepatitis B, C, and E virus infections in patients with haematological malignancies and those undergoing haematopoietic cell transplantation: recommendations from the 9th European Conference on Infections in Leukaemia (ECIL-9) [Consensus].
- Treatment of Invasive Pulmonary Aspergillosis and Preventive and Empirical Therapy for Invasive Candidiasis in Adult Pulmonary and Critical Care Patients An Official American Thoracic Society Clinical Practice Guideline.
European guidelines on treatment and supportive measures in chronic neutropenias: A consensus between the European Hematology Association and the EuNet‐INNOCHRON COST Action based on a systematic evidence review.
News of the Week– April 28, 2025 (CLICK TO VIEW)
- Characterization of the phenotypic consequences of the Duffy-null genotype [Retrospective study]
- Venetoclax schedule in AML: 7 vs. 14 vs. 21 vs. 28 days [Editorial]
- Updated Definition and Scoring of Disseminated Intravascular Coagulation in 2025: Communication from the ISTH SSC Subcommittee on Disseminated Intravascular Coagulation [Consensus]
- What is radiation-induced acute myeloid leukemia/can it be accurately identified? [Perspective]
- Genetic subtypes of B-cell acute lymphoblastic leukemia in adults [Review]
News of the Week– April 17, 2025 (CLICK TO VIEW)
- Use of machine learning techniques to predict poor survival after hematopoietic cell transplantation for myelofibrosis [Chronic Malignancies Working Party Session]
- The Phase 2 STARGAZE Trial of the Glucagon-like Peptide 2 (GLP-2) Analog Apraglutide in Combination with Ruxolitinib for Steroid-Refractory Gastrointestinal (GI) Acute Graft-Versus-Host Disease (aGvHD): Comparisons with a MAGIC Control Cohort [Presidential Symposium]
- EBMT consensus on allogeneic transplantation in T-cell lymphoma [Lymphoma Working Party Session]
- Role of allo-HCT in ‘non-classical’ MPNs and MDS/MPNs: recommendations from the PH&G Committee and the CMWP of the EBMT [Chronic Malignancies Working Party Session]
- Update on the recommendations of the 10th European Conference on Infections in Leukaemia (ECIL) [Infectious Diseases Working Party Session]
News of the Month– April 7, 2025 (CLICK TO VIEW)
- Hematopoietic cell transplantation for older acute myeloid leukemia patients in first complete remission: results of a randomized phase III study [clinical trial]
- Role of Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive B-Cell Acute Lymphoblastic Leukemia in the Contemporary Era [Review]
- Trends in allogeneic transplantation for favorable risk acute myeloid leukemia in first remission: a longitudinal study of >15 years from the ALWP of the EBMT [Retrospective study]
- Optimal timing and impact of allogeneic peripheral blood stem cell transplantation in adult T-cell lymphoblastic lymphoma: insights from a large cohort multi-center real-world study in Shanghai [Retrospective study]
- Budesonide, Added to PTCy-Based Regimen, for Prevention of Acute GI GVHD After Allogeneic Stem Cell Transplantation [Observational Study]
- Autologous hematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder — recommendations from ECTRIMS and the EBMT [Guidelines]
- Factors associated with survival following allogeneic transplantation for myeloid neoplasms harboring TP53 mutations [Retrospective Study]
- Luspatercept for the treatment of anemia in allo-HSCT for patients with hematological diseases [Letter to the Editor]
- Low rates of chronic graft-versus-host disease with ruxolitinib maintenance following allogeneic HCT [Clinical Trial]
- Allogeneic Stem Cell Transplantation in Participants With Hematologic Malignancies Following Pembrolizumab Therapy [Retrospective study]
- Implications of lymphocyte kinetics after chimeric antigen receptor T cell therapy for multiple myeloma [Letter to the Editor]
News of the Week– March 23, 2025 (CLICK TO VIEW)
- Ruxolitinib combined with dexamethasone in newly diagnosed adult hemophagocytic lymphohistiocytosis patients in China [Phase 2 clinical trial]
- Impact of calreticulin mutations on treatment and survival outcomes in myelofibrosis during ruxolitinib therapy [Retrospective study].
- Itacitinib for the Prevention of IEC Therapy–Associated CRS: Results From the Two-Part Phase 2 INCB 39110-211 Study.
- Enterocolitis associated with glofitamab—First report and clinicopathological findings in three cases.
- Waldenström Macroglobulinemia: 2025 Update on Diagnosis, Risk Stratification, and Management [Review].
News of the Week– March 16, 2025 (CLICK TO VIEW)
- BCMA-directed CAR T-cell therapy in patients with multiple myeloma and CNS involvement [Retrospective study]
- Impact of treatment for adolescent and young adults with essential thrombocythemia and polycythemia vera [Retrospective study].
- Efficacy of Combined CD38 and PD1 Inhibition with Isatuximab and Cemiplimab in Relapsed/Refractory NK/T-Cell Lymphoma [Phase II trial]
- Consensus recommendations from the 2024 Lymphoma Research Foundation workshop on treatment selection and sequencing in CLL or SLL
News of the Week– March 11, 2025 (CLICK TO VIEW)
- Improved Outcomes of Myeloma Cast Nephropathy in Newly Diagnosed Multiple Myeloma With Modern Anti-Myeloma Therapies [Retrospective study].
- Methylation sequencing enhances the interpretation of clonal hematopoiesis dynamics [Basic research: Letter to the Editor].
- Role of azathioprine in the management of ITP in the TPO-RA era: a single-center retrospective study.
- Vodobatinib for patients with Philadelphia chromosome-positive chronic myeloid leukemia resistant or intolerant to multiple lines of previous therapy: an open-label, multicentre, phase 1/2 trial [Clinical trial].
- Long-term outcomes of tyrosine kinase inhibitors in chronic myeloid leukemia [Review Series]
News of the Week– March 2, 2025 (CLICK TO VIEW)
- Co-occurrence of Cytogenetic Abnormalities and High-Risk Disease in Newly Diagnosed and Relapsed/Refractory Multiple Myeloma [Systematic review].
- Outcomes of patients with relapsed or refractory primary mediastinal B‐cell lymphoma treated with anti‐CD19 CAR‐T cells: CARTHYM, a study from the French national DESCAR‐T registry [Retrospective study].
- Genomic landscape of testicular follicular lymphoma is characterized by frequent 1p36/TNFRSF14 alterations [Case series].
- Serum free light chains in a racially diverse population including African Americans and populations from South Africa [Retrospective study].
- How I treat iron-refractory iron deficiency anemia—An expert opinion-based treatment guidance for children and adults [Review]
News of the Month– February 26, 2025 (CLICK TO VIEW)
- Single versus tandem autologous stem cell transplantation in newly diagnosed multiple myeloma [observational study]
- Utility of the 2024 best practice recommendations from the EBMT Cellular Therapy and Immunobiology Working Party for use of donor lymphocyte infusions after allogeneic hematopoietic stem cell transplantation [Correspondence].Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation [Letter to the editor].
- Incidence, risk factors, and outcomes of BK hemorrhagic cystitis in hematopoietic stem cell transplantation from HLA-matched and haploidentical donors with post-transplant cyclophosphamide [Retrospective study].
- UK consensus statement on the use of plerixafor in healthy stem cell donors [Letter to the editor].
- Measurable residual disease as predictor of post–day +100 relapses after allografting in adult AML [Retrospective Study]
- Clearance of Driver Mutations after Transplantation for Myelofibrosis [Retrospective study].
- Pre-Transplant MRD Does Not Seem to Impact Survival in NPM1-Mutated AML Undergoing Allogeneic Stem Cell Transplantation [Retrospective Study]
- aGvHDtrackR and cGvHDtrackR: shiny applications for graft versus host disease management and clinical data collection [Clinical Application]
- Safety and efficacy of the ROCK-2-inhibitor Belumosudil in cGvHD treatment – a retrospective, German-Swiss multicenter real-world data analysis [Retrospective Cohort]
- Hematopoietic cell transplantation soon after first relapse in acute myeloid leukemia [Pros and Cons Editorial].
- A phase 2 multicenter trial of ruxolitinib to treat bronchiolitis obliterans syndrome after allogeneic HCT [Clinical trial].
News of the Week– February 23, 2025 (CLICK TO VIEW)
- Zanubrutinib for the treatment of Bing–Neel syndrome [Case series].
- How I treat patients who are refractory to platelet transfusions [Review].
- Diagnosis, management, and outcomes of drug-induced erythrocytosis: A systematic review.
- Clinically relevant bleeding according to location of metastases in cancer-associated thrombosis [Retrospective study].
- Clinical-genomic profiling of MDS to inform allo-HSCT: Recommendations from an international panel on behalf of the EBMT
News of the Week– February 16, 2025 (CLICK TO VIEW)
- Asciminib plus dasatinib and prednisone for Philadelphia chromosome-positive acute leukemia [Phase 1 clinical trial].
- Ibrutinib plus venetoclax in relapsed or refractory mantle cell lymphoma (SYMPATICO): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study [clinical trial].
- VITT-like Monoclonal Gammopathy of Thrombotic Significance [Case series].
- CAR+ T-Cell Lymphoma after Cilta-cel Therapy for Relapsed or Refractory Myeloma [Case series].
European Myeloma Network Group Review and Consensus Statement on Primary Plasma Cell Leukemia [Guidelines].
News of the Week– February 10, 2025 (CLICK TO VIEW)
- Clinical impact of [18F]FDG-PET/CT in ARI0002h treatment, a CAR-T against BCMA for relapsed/refractory multiple myeloma [Retrospective study].
- Fixed-Duration Acalabrutinib Combinations in Untreated Chronic Lymphocytic Leukemia [Phase 3 clinical trial].
- CD4+ T-Cell Lymphoma Harboring a Chimeric Antigen Receptor Integration in TP53 [Case report].
- Hemophagocytic Lymphohistiocytosis [Review].
News of the Week– February 4, 2025 (CLICK TO VIEW)
- Risk of hospitalization with infection in adults with primary AIHA treated with rituximab: a French nationwide study [Retrospective study].
- How I treat iron overload in adult MDS [Review].
- International myeloma working group immunotherapy committee recommendation on sequencing immunotherapy for treatment of multiple myeloma [Consensus].
- Prognostic impact of expression of CD2, CD25, and/or CD30 in/on mast cells in systemic mastocytosis: a registry study of the European Competence Network on Mastocytosis [Retrospective study].
- Prospective Pharmacokinetic Evaluation of Venetoclax in AML Supports Re-Evaluation of Recommended Dose Adjustments With Azole Antifungals [Prospective study].
News of the Week– January 27, 2025 (CLICK TO VIEW)
- How We Treat Anemia in Myelofibrosis [Review].
- Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation [Phase 2b clinical trial].
- Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone Induction in Newly Diagnosed Myeloma: Analysis of the MIDAS Trial [Phase III clinical trial].
- JAK1/2 inhibitor ruxolitinib for treating systemic chronic active Epstein-Barr virus disease [Phase 2 clinical trial].
- Safety and efficacy of pegcetacoplan treatment for cold agglutinin disease and warm antibody autoimmune hemolytic anemia [Phase 2 clinical trial].
News of the Week– January 20, 2025 (CLICK TO VIEW)
- AML typical mutations (CEBPA, FLT3, NPM1) identify a high-risk chronic myelomonocytic leukemia independent of CPSS molecular [Retrospective study].
- Hypomethylating agents for patients with VEXAS without myelodysplastic syndrome: Clinical outcome and longitudinal follow-up of vacuolization and UBA1 clonal dynamics [Case series].
- Surrogate endpoints in mature B-cell neoplasms – meaningful or misleading? [Perspective].
- The Heterogeneous Syndrome of Noninfectious Causes of Persistent Fever in Neutropenic Patients With Hematologic Malignancy: Another Opportunity for Stewardship? [Commentary].
- How I Treat Higher-Risk MDS [Review].
News of the Month– January 15, 2025 (CLICK TO VIEW)
- Decision analysis for transplant candidates with primary myelofibrosis in the ruxolitinib era [decision analysis study]
- Biomarker-derived fast-and-frugal decision tree for preemption of veno-occlusive disease/sinusoidal obstructive syndrome [Letter to the editor].
- Clinical and Immune Effects of Peri-Transplantation JAK Inhibition for Myelofibrosis [Retrospective observational study].
- Allogeneic hematopoietic stem-cell transplantation for patients with Richter transformation: a retrospective study on behalf of the Chronic Malignancies Working Party of the EBMT [Retrospective study].
- Ruxolitinib for pediatric patients with treatment-naïve and steroid-refractory acute graft-versus-host disease: the REACH4 study [Clinical Trial].
- Novel machine learning technique further clarifies unrelated donor selection to optimize transplantation outcomes [Retrospective Study].
- A systematic review and meta-analysis of HHV-6 and mortality after hematopoietic cell transplant
- High activity of the new myeloablative regimen of gemcitabine/clofarabine/busulfan for allogeneic transplant for aggressive lymphomas [Clinical Trial].
- Emapalumab therapy for hemophagocytic lymphohistiocytosis before reduced-intensity transplantation improves chimerism [Retrospective Study].
- Autologous stem cell transplantation in T-cell/histiocyte-rich large B-cell lymphoma: EBMT Lymphoma Working Party study [Retrospective study].
- Role of molecular alterations in transplantation decisions for patients with primary myelofibrosis [Retrospective Study].
- Artificial intelligence enabled interpretation of ECG images to predict hematopoietic cell transplantation toxicity. [Retrospective Study].
- Optimal infused CD34+ cell dose in multiple myeloma patients undergoing upfront autologous hematopoietic stem cell transplantation [Retrospective Study].
- Autologous stem cell transplantation for multiple patients whose myeloma-defining event was SLiM [Retrospective study].
News of the Week– January 13, 2025 (CLICK TO VIEW)
- Talquetamab plus Teclistamab in Relapsed or Refractory Multiple Myeloma [Clinical trial].
- Brentuximab Vedotin Combination for Relapsed Diffuse Large B-Cell Lymphoma [Clinical trial].
- Clearance of Driver Mutations after Transplantation for Myelofibrosis [Retrospective study].
- T cell malignancies after CAR T cell therapy in the DESCAR-T registry [Retrospective study].
- Diagnosis and management of monoclonal gammopathy of renal significance: A British Society for Haematology good practice paper [Guideline].
News of the Week– January 6, 2025 (CLICK TO VIEW)
- Primary Large B-cell Lymphomas of Immune-Privileged Sites [Review]
- How I Treat Sickle Cell Disease with Gene Therapy [Review]
- Integration of Clinical Outcomes and Molecular Features in Extramedullary Disease in Multiple Myeloma [Retrospective Study]
Identification of Factors Predicting Low-Risk Febrile Neutropenia Admissions in Adults with Acute Myeloid Leukemia [Retrospective Study]
News of the Week– December 30, 2024 (CLICK TO VIEW)
- The genomic and clinical consequences of replacing procarbazine with dacarbazine in escalated BEACOPP for Hodgkin lymphoma [Retrospective study].
- Real-World Safety and Health Care Resource Utilization of Teclistamab Under an Outpatient Model for Step-Up Dosing Administration [Retrospective study].
- Efficacy and Safety of Venetoclax Plus Azacitidine for Patients With Treatment-Naive High-Risk Myelodysplastic Syndromes [Phase 1 clinical trial].
- Clinical interrogation of TP53 aberrations and its impact on survival in patients with myeloid neoplasms [Retrospective study].
- The significance of free light-chain ratio in light-chain monoclonal gammopathy of undetermined significance: a flow cytometry sub-study of the iStopMM screening study [Retrospective study].
News of the Week– December 16, 2024 (CLICK TO VIEW)
- Daratumumab or Active Monitoring for High-Risk Smoldering Multiple Myeloma.
- Belantamab Mafodotin, Bortezomib, and Dexamethasone Vs. Daratumumab, Bortezomib, and Dexamethasone in Relapsed/Refractory Multiple Myeloma: Overall Survival Analysis and Updated Efficacy Outcomes of the Phase 3 Dreamm-7 Trial.
- Effects of Intravenous Immunoglobulin Supplementation (IVIG) on Infections in Recipients of Teclistamab Therapy for Multiple Myeloma (MM): A Multi-Institutional Study.
- Ibrutinib-Rituximab Is Superior to Rituximab-Chemotherapy in Previously Untreated Older Mantle Cell Lymphoma Patients: Results from the International Randomised Controlled Trial, Enrich.
- Lack of Benefit of Autologous Hematopoietic Cell Transplantation (auto-HCT) in Mantle Cell Lymphoma (MCL) Patients (pts) in First Complete Remission (CR) with Undetectable Minimal Residual Disease (uMRD): Initial Report from the ECOG-ACRIN EA4151 Phase 3 Randomized Trial.
- Tafasitamab Plus Lenalidomide and Rituximab for Relapsed or Refractory Follicular Lymphoma: Results from a Phase 3 Study (inMIND).
- Updated Results and Longer Follow-up from the AUGMENT-101 Phase 2 Study of Revumenib in All Patients with Relapsed or Refractory (R/R) KMT2Ar Acute Leukemia.
- Long-Term Response Analysis of Transfusion Independence in Erythropoiesis Stimulating Agent–Naive Patients with Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes Treated with Luspatercept Vs. Epoetin Alfa in the COMMANDS Trial.
- Extended Treatment of Venous Thromboembolism with Reduced- Vs. Full-Dose Direct Oral Anticoagulants in Patients at High Risk of Recurrence.
- Identification of Hepatic-like Erythropoietin with Enhanced Activity As a New Cause of Hereditary and Acquired Erythrocytosis.
News of the Month– December 6, 2024 (CLICK TO VIEW)
- The Role of Pre-existing Anti-HLA Antibodies in Severe Aplastic Anemia Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation [Retrospective study].
- Autologous Hematopoietic Cell Transplantation Consolidation for First Response is Associated with Longer Survival Among Patients with Nodal Peripheral T Cell Lymphoma [Retrospective study].
- Ixazomib as consolidation and maintenance versus observation in patients with relapsed multiple myeloma after salvage autologous hematopoietic stem-cell transplantation [(Myeloma XII [ACCoRD]): interim analysis of a multicenter, open-label, randomized, phase 3 trial].
- Induction prior autologous hematopoietic cell transplantation in multiple myeloma [Review].
- Evaluation of prognostic factors in patients with high-risk classical Hodgkin lymphoma undergoing autologous transplantation [Retrospective study].
- ASTCT and USCLC Clinical Practice Recommendations for Allogeneic Stem Cell Transplant in Mycosis Fungoides and Sézary Syndrome [Guideline].
- Influence of comorbidities on outcome in 1102 patients with an allogeneic hematopoietic stem cell transplantation [Retrospective study].
- Best Practice Considerations by The American Society of Transplant and Cellular Therapy: Infection Prevention and Management After Chimeric Antigen Receptor T Cell Therapy for Hematological Malignancies [Guideline].
- Interplay between donor age and HLA-DP matching in 10/10 HLA-matched unrelated donor HCT [Retrospective study].
- Outcomes of frail patients undergoing high-dose chemotherapy and autologous stem cell transplantation for multiple myeloma [Retrospective study].
- Long-term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium [Retrospective study].
- Non-cryopreserved autologous peripheral blood stem cell transplantation for multiple myeloma and lymphoma in countries with limited resources: practice considerations from the Worldwide Network for Blood and Marrow Transplantation [Systematic review and meta-analysis].
News of the Week – December 2, 2024 (CLICK TO VIEW)
- Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study [Phase 2 clinical trial].
- Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia [Phase 1b–2 clinical trial].
- Ibrutinib in Early-Stage Chronic Lymphocytic Leukemia: The Randomized, Placebo-Controlled, Double-Blind, Phase III CLL12 Trial [Phase 3 clinical trial].
- Acute Leukemias of Ambiguous Lineage With MDS-Associated Mutations Show Similar Prognosis Compared to Acute Myeloid Leukemia With MDS-Associated Mutations: A Study From the Bone Marrow Pathology Group [Retrospective study].
- Indeterminate DC histiocytosis is distinct from LCH and often associated with other hematopoietic neoplasms [Retrospective study].
- Delaying pegaspargase during induction in adults with acute lymphoblastic leukaemia is associated with lower risk of high-grade hepatotoxicity without adversely impacting outcomes [Retrospective study].
Development of hyperdiploidy starts at an early age and takes a decade to complete [Basic research].
News of the Week – November 25, 2024 (CLICK TO VIEW)
- Retreatment of Multiple Myeloma with Previously Refractory Drugs [Retrospective study].
- Prognostic risk and survival of asymptomatic IgM monoclonal gammopathy: Results from a Spanish Multicenter Registry [Retrospective study].
- How I approach the treatment of thrombotic complications in patients with myeloproliferative neoplasms [Review].
- JAK2-mutant clonal hematopoiesis is associated with venous thromboembolism [Retrospective study].
- Prevention and Treatment of Cancer-Related Infections, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology [Guideline].
News of the Week – November 17, 2024 (CLICK TO VIEW)
- Severe ICANS after CAR T-cell therapy and assessment of prevention with levetiracetam for seizure prophylaxis following CAR T-cell for DLBCL & PMBCL in Europe: a survey on behalf of the Cellular Therapy & Immunobiology Working Party (CTIWP) of the EBMT [Descriptive study]
- Comparison of EasyM, a clonotypic mass spectrometry assay, and EuroFlow minimal residual disease assessment in multiple myeloma [Retrospective study]
- Proteasome inhibitors related thrombotic microangiopathy: a systematic and comprehensive review [Systematic review]
- Ruxolitinib-based regimen in children with autoimmune or autoinflammatory disease-related haemophagocytic lymphohistiocytosis [Retrospective study]
- Johnson & Johnson submits applications in the U.S. and EU seeking approval of DARZALEX FASPRO® / DARZALEX® as subcutaneous monotherapy for high-risk smoldering multiple myeloma [News drug-regulation]
- FDA-approves obecabtagene autoleucel for adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia [News drug regulation]
News of the Week – November 10, 2024 (CLICK TO VIEW)
- A modern view of LGL leukemia [Review]
- Risk prediction for clonal cytopenia: multicenter real-world evidence [Retrospective study]
- The use of direct oral anticoagulants in the secondary prevention of venous thromboembolism in patients with severe thrombophilia: communication from the ISTH SSC Subcommittee on Physiological Anticoagulants and Thrombophilia [Narrative review]
- Assessment of fitness for bleomycin use and management of bleomycin pulmonary toxicity in patients with classical Hodgkin lymphoma: A British Society for Haematology Good Practice Paper [Guideline]
- Acute Promyelocytic Leukemia: Long-Term Outcomes from the HARMONY Project [Retrospective study]
News of the Week – November 3, 2024 (CLICK TO VIEW)
- Isatuximab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma [Clinical trial]
- Proposals for revised International Working Group–European LeukemiaNet criteria for anemia response in myelofibrosis [Consensus]
- Valemetostat for patients with relapsed or refractory peripheral T-cell lymphoma (VALENTINE-PTCL01): a multicentre, open-label, single-arm, phase 2 study [Clinical trial]
- Zanubrutinib, Obinutuzumab, and Venetoclax for First-Line Treatment of Mantle Cell Lymphoma with a TP53 Mutation [Clinical trial]
- Molecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in multiple myeloma [Retrospective and basic research study]
- Intensive chemotherapy after hypomethylating agent and venetoclax in adult acute myeloid leukemia [Retrospective study]
News of the Month – October 29, 2024 (CLICK TO VIEW)
- Randomized Phase III SIERRA Trial of 131I-Apamistamab Before Allogeneic Hematopoietic Cell Transplantation Versus Conventional Care for Relapsed/Refractory AML [Clinical trial]
- Daratumumab with lenalidomide as maintenance after transplant in newly diagnosed multiple myeloma: the AURIGA study [Clinical trial]
- Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD [Retrospective study]
- Long-Term Follow-Up of the Prospective Randomized AATT Study (Autologous or Allogeneic Transplantation in Patients With Peripheral T-Cell Lymphoma) [Prospective study]
- Comparison of Thiotepa-based Conditioning Regimens for Older Adults with Primary Diffuse Large B-cell Lymphoma of the Central Nervous System (PCNSL) Undergoing Autologous Hematopoietic Cell Transplantation (Auto-HCT) [Retrospective study]
- Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia in Adults Over 70 Years Old [Review]
- ASTCT Consensus Recommendations on Testing and Treatment of Patients with Donor-specific Anti-HLA Antibodies [Consensus]
- High-dose chemotherapy with autologous stem cell transplants in adult primary non-seminoma mediastinal germ-cell tumors. A report from the Cellular Therapy and Immunobiology working party of the EBMT [Retrospective study]
- Allogeneic Hematopoietic Cell Transplantation for the Treatment of Severe Aplastic Anemia: Evidence-Based Guidelines from the American Society for Transplantation and Cellular Therapy [Guidelines]
- Late cytomegalovirus disease after hematopoietic cell transplantation: significance of novel transplantation techniques
- CMV reactivation during pre transplantation evaluation: a novel risk factor for post transplantation CMV reactivation [Retrospective study]
- CD70 identifies alloreactive T cells and represents a potential target for prevention and treatment of acute graft versus host disease [Basic and clinical research]
- Transplant for myelodysplastic neoplasms [Retrospective study]
- Allogeneic stem cell transplantation in de novo core-binding factor acute myeloid leukemia in first complete remission [Retrospective study]
News of the Week – October 27, 2024 (CLICK TO VIEW)
- Nivolumab + AVD in Advanced-Stage Classic Hodgkin’s Lymphoma [Phase 3 clinical trial]
- Outcomes After Brexucabtagene Autoleucel Administered as a Standard Therapy for Adults With Relapsed/Refractory B-Cell ALL [Retrospective study]
- Rapid high-dose cyclophosphamide as bridging treatment for advanced therapies in multiple myeloma [Retrospective study]
- Efficacy of intravenous high-dose methotrexate in preventing relapse to the central nervous system in R-CHOP(-like)-treated, high-risk, diffuse large B-cell lymphoma patients and its effect on mortality [Systematic review and meta-analysis]
- How I Treat Older Patients with Relapsed/ Refractory Diffuse Large B Cell Lymphoma [Review article]
News of the Week – October 20, 2024 (CLICK TO VIEW)
- Histiocytosis of the orbit and its association with KRAS mutations [Retrospective study]
- Testicular large B‐cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCL [Retrospective study]
- How I Treat: Maintenance Therapy in Acute Myeloid Leukemia [Review]
- How I treat Blastic Plasmacytoid Dendritic Cell Neoplasm [Review]
- Hairy-Cell Leukemia [Review]
News of the Week – October 13, 2024 (CLICK TO VIEW)
- Aggressive Lymphoma after CD19 CAR T-Cell Therapy [Case report]
- Minimally Invasive Assessment of Peripheral Residual Disease During Maintenance or Observation in Transplant-Eligible Patients With Multiple Myeloma [Retrospective study]
- Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange [Retrospective study]
- Febrile Neutropenia in Patients with Duffy-null Associated Neutrophil Counts and Multiple Myeloma or AL amyloidosis [Retrospective study]
- How I diagnose and treat cardiorespiratory complications of transfusion [Review]
News of the Week – October 6, 2024 (CLICK TO VIEW)
- Dexamethasone dose intensity does not impact outcomes in newly diagnosed multiple myeloma: a secondary SWOG analysis [Retrospective study]
- Intrathecal chemotherapy as treatment for chimeric antigen receptor T cell (CAR T) therapy associated neurotoxicity [Retrospective study]
- PHF6 mutations in chronic myelomonocytic leukemia identify a unique subset of patients with distinct phenotype and superior prognosis [Retrospective study]
- Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial [Clinical trial]
- Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B
News of the Week – September 29, 2024 (CLICK TO VIEW)
- Venetoclax plus decitabine as a bridge to allogeneic hematopoietic stem-cell transplantation in older patients with acute myeloid leukemia (VEN-DEC GITMO): final report of a multicenter, single-arm, phase 2 trial [Clinical trial]
- Risk of Bleeding in Essential Thrombocythemia Patients with Extreme Thrombocytosis [Retrospective study]
- Pomalidomide for Epistaxis in Hereditary Hemorrhagic Telangiectasia [Clinical trial]
- Intensive induction chemotherapy vs hypomethylating agents in combination with venetoclax in NPM1-mutant AML [Retrospective study]
- Transformation of marginal zone lymphoma to Hodgkin lymphoma [Case series study]
- Multiomics analysis of IgM monoclonal gammopathies reveals epigenetic influence on oncogenesis via DNA methylation [Basic and prospective research]
- Measurable Residual Disease by Mass Spectrometry and Next-Generation Flow to Assess Treatment Response in Myeloma [Retrospective study]
- Axatilimab in Recurrent or Refractory Chronic Graft-versus-Host Disease [Clinical trial]
News of the Week – September 15, 2024 (CLICK TO VIEW)
- Atezolizumab, venetoclax, and obinutuzumab combination in Richter transformation diffuse large B-cell lymphoma (MOLTO): a multicentre, single-arm, phase 2 trial
- TP53 Mutated Acute Myeloid Leukemia: How Can We Improve Outcomes?
- Advanced imaging for earlier diagnosis and morbidity prevention in multiple myeloma: A British Society of Haematology and UK Myeloma Society Good Practice Paper
- Outcomes of patients with primary central nervous system lymphoma following CD19-targeted chimeric antigen receptor T-cell therapy
News of the Week – September 8, 2024 (CLICK TO VIEW)
- Risk Stratification in Older Intensively Treated Patients With AML
- Prognostic impact of cytogenetic abnormalities by FISH in AL amyloidosis with daratumumab-based frontline therapy
- Mass spectrometry-based assessment of M protein in peripheral blood during maintenance therapy in multiple myeloma
- Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations
- Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies
News of the Month – September 4, 2024 (CLICK TO VIEW)
- Second Allogeneic Hematopoietic Cell Transplantation for Relapsed Adult Acute Myeloid Leukemia
- How risky is a second allogeneic stem cell transplantation?
- Efficacy of Autologous and Allogeneic Hematopoietic Cell Transplantation in Adults with Acute Promyelocytic Leukemia
- Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors
- Autologous transplant vs. CAR-T therapy in patients with DLBCL treated while in complete remission
- PTCy vs CNI–based GVHD prophylaxis in HLA-matched transplants for Hodgkin lymphoma: a study of the LWP of the EBMT
- Haploidentical transplantation in primary refractory/relapsed secondary vs de novo AML: from the ALWP/EBMT
- Isocitrate dehydrogenase (IDH) 1 and 2 mutations predict better outcome in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation: a study of the ALWP of the EBMT
- Human Leukocyte Antigen Mismatching and Survival in Contemporary Hematopoietic Cell Transplantation for Hematologic Malignancies
- Transplantation in Adult Patients with Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis: Yes or No?
- Melphalan Dose in Combination with Fludarabine Affects GI Toxicity and GVHD after Allogeneic Transplantation in Acute Myeloid Leukemia and Myelodysplastic Syndromes
- A Multicenter Phase II Trial of Ruxolitinib for Treatment of Corticosteroid Refractory Sclerotic Chronic Graft-Versus-Host Disease
- Long-term outcomes of peripheral blood stem cell unrelated donors mobilized with filgrastim
- First-line treatment of severe aplastic anemia: immunosuppressive therapy plus eltrombopag versus haploidentical hematopoietic stem cell transplantation, a multicenter prospective study
- Early Toxicity and Efficacy of Four Different Conditioning Regimens for Autologous Hematopoietic Cell Transplantation in Patients With Lymphoma: Impact of Drug Shortages in a Resource-Constrained Country
News of the Month – August 2, 2024 (CLICK TO VIEW)
- Long-term outcomes after haploidentical stem cell transplantation for hematologic malignancies.
- Post-transplant cyclophosphamide compared to sirolimus/ tacrolimus in reduced intensity conditioning transplants.
- Cyclophosphamide and thiotepa increases risk of transplant-associated thrombotic microangiopathy.
- Clinical Practice Recommendations for Hematopoietic Cell Transplantation and Cellular Therapies in Follicular Lymphoma.
- An international learning collaborative phase 2 trial for haploidentical bone marrow transplant in sickle cell disease.
- Clonal Hematopoiesis and Therapy-Related Myeloid Neoplasms (t-MN) After Autologous Transplant for Hodgkin Lymphoma (HL).
- Clonal relapse dynamics in acute myeloid leukemia (AML) following allogeneic hematopoietic cell transplantation (alloHCT).
- Alternative donor transplantation for severe aplastic anemia (SAA): a comparative study of the SAAWP EBMT.
- Continuously improving outcome over time after second allogeneic stem cell transplantation (alloSCT2) in relapsed acute myeloid leukemia (AML): an EBMT registry analysis of 1540 patients.
- Combination of anti-thymocyte globulin (ATG) with post-transplant cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis in patients undergoing haploidentical hematopoietic stem cell transplantation (haplo-HSCT): systematic review and meta-analysis.
- Tandem Autologous Stem Cell Transplantation Does Not Benefit High-Risk Myeloma Patients In The Maintenance Era: Real-world Results From The Canadian Myeloma Research Group Database.
- Does IPSS-R downstaging before transplantation improve the prognosis of patients with myelodysplastic neoplasms?
- Abatacept for acute graft-versus-host disease prophylaxis after unrelated donor hematopoietic cell transplantation (HCT).
- Assessing the efficacy of allogeneic hematopoietic cell transplantation (Allo-HCT) in VEXAS syndrome: results of a systematic review and meta-analysis.
News of the Week – July 28, 2024 (CLICK TO VIEW)
- E1910 trial: Blinatumomab for measurable residual disease (MRD)-negative B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in adults.
- Low dose lenalidomide versus placebo in non-transfusion dependent patients with low risk, del(5q) myelodysplastic syndromes (SintraREV): a randomised, double-blind, phase 3 trial.
- Optimizing the Post-CAR T Monitoring Period for Axicabtagene Ciloleucel, Tisagenlecleucel, and Lisocabtagene Maraleucel.
- Clinical Outcomes After Idecabtagene Vicleucel in Older Multiple Myeloma Patients: A Multicenter Real-world Experience.
- How I (Diagnose and) Treat Myeloid / Lymphoid Neoplasms (MLN) with Tyrosine Kinase (TK) Gene Fusions.
News of the Week – July 21, 2024 (CLICK TO VIEW)
- CD22-directed chimeric antigen receptor (CAR) T-cell therapy (CAR22) for large B-cell lymphomas (LBCL) progressing after CD19-directed CAR T-cell therapy (CAR19): a dose-finding phase 1 study.
- Improved prevention and treatment strategies for differentiation syndrome (DS) contribute to reducing early mortality in patients with acute promyelocytic leukemia (APL): a clinical trial.
- Response-Adapted Ultralow-Dose Radiation Therapy (RT) for Orbital Indolent B-Cell Lymphoma (BCL): A Phase 2 Nonrandomized Controlled Trial.
- An open-label, prospective trial to evaluate the efficacy and safety of ixazomib in combination with cyclophosphamide and dexamethasone (ICD) in patients with newly diagnosed POEMS syndrome.
- The origin of ferritin reference intervals: a systematic review.
News of the Week – July 14, 2024 (CLICK TO VIEW)
- Clinical trial in advanced-stage classical Hodgkin lymphoma (HL): BrECADD versus eBEACOPP.
- Low-Dose Planned Glucarpidase Allows Safe Outpatient High-Dose Methotrexate (HD-MTX )Treatment for central nervous system (CNS) Lymphoma. A prospective nonrandomized study.
- Mitral regurgitation (MR) is associated with similar loss of von Willebrand factor (VWF) large multimers, but lower frequency of anemia compared with aortic stenosis (AS).
- A systematic review and meta-analysis of nonrelapse mortality (NRM) after chimeric antigen receptor (CAR) T-cell therapy.
- How I Treat: Differentiation Therapy in Acute Myeloid Leukemia (AML).
News of the Week – July 7, 2024 (CLICK TO VIEW)
- Venetoclax and hypomethylating (VEN-HMA) agents in octogenarians and nonagenarians with acute myeloid leukemia (AML).
- Efficacy and safety of bendamustine‐containing bridging therapy (BT) in relapsed/refractory (R/R) large B‐cell lymphoma (LBCL) patients receiving CD19 chimeric antigen receptor (CAR) T-cells.
- Molecular diagnosis of primary CNS lymphoma (PCNSL) in 2024 using MYD88Leu²⁶⁵Pro and IL-10.
- Response and resistance to menin inhibitor in upstream binding transcription factor (UBTF-TD) acute myeloid leukemia (AML).
- Pembrolizumab and low-dose, single-fraction radiotherapy (RT) for patients with relapsed or refractory multiple myeloma (RRMM).
News of the Month- July 4, 2024 (CLICK TO VIEW)
- Post-transplant cyclophosphamide (PTCy) at 80 mg/kg with low dose post-engraftment anti-thymocyte globulin (ATG) in haploidentical transplantation (Haplo-HCT) with myeloablative conditioning (MAC).
- Younger unrelated donors may be preferable over HLA match in the post-transplant cyclophosphamide (PTCy) era: a study from the ALWP of the EBMT.
- Harmonizing definitions for hematopoietic recovery, graft rejection, graft failure, poor graft function, and donor chimerism in allogeneic hematopoietic cell transplantation.
- How I diagnose and treat organizing pneumonia in hematopoietic cell transplant recipients.
- Yttrium-90 Anti-CD25-BEAM-Conditioning for Autologous Hematopoietic Cell Transplantation (AHCT) in Peripheral T Cell Lymphoma (PTCL).
- Vedolizumab for the prevention of intestinal acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT): a randomized phase 3 trial.
- Evaluation of European LeukemiaNet (ELN) 2022 risk classification in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HCT) for acute myeloid leukemia (AML): Identification of a very poor prognosis genetic group.
- Prognostic factors impacting post-transplant outcomes in adult T-cell acute lymphoblastic leukemia (T-ALL): a registry-based study by the EBMT acute leukemia working party.
- Anti-thymocyte globulin (ATG) or post-transplant cyclophosphamide to prevent graft-versus-host disease (GVHD) in matched unrelated donor (MUD) allogeneic hematopoietic stem cell transplantation (allo-HSCT)?
- Neurologic Complications of the Central Nervous System after Allogeneic Stem Cell Transplantation (AlloSCT): The Role of Transplantation-Associated Thrombotic Microangiopathy as a Potential Underreported Cause.
- Racial/ethnic disparities in availability of volunteer unrelated donors for allogeneic stem cell transplantation (AlloSCT).
- Autologous stem cell boost improves persistent immune effector cell associated hematotoxicity following BCMA directed chimeric antigen receptor (CAR) T-cell therapy in multiple myeloma (MM).
- Myeloablative vs nonmyeloablative consolidation for primary central nervous system lymphoma (PCNSL): results of Alliance 51101.
- Graft Failure (GF) Incidence, Risk Factors, and Outcomes in Patients Undergoing Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation (AlloSCT) Using Post-Transplant Cyclophosphamide (PTCy).
News of the Week – June 30, 2024 (CLICK TO VIEW)
- Linvoseltamab for Treatment of Relapsed/Refractory Multiple Myeloma (RRMM).
- Brigatinib in Anaplastic lymphoma kinase (ALK)–positive anaplastic large-cell lymphoma (ALCL) after Failure of Brentuximab Vedotin
- Epcoritamab monotherapy in patients with relapsed or refractory follicular lymphoma (EPCORE NHL-1).
- Risk of second tumors and T-cell lymphoma after chimeric antigen receptor (CAR) T-cell therapy.
- Long-term pharmacodynamic and clinical effects of twice- versus once-daily low-dose aspirin in essential thrombocythemia (ET).
- Serum mass spectrometry for treatment monitoring in patients with relapsed/refractory multiple myeloma (RRMM) receiving chimeric antigen receptor (CAR) T-cells.
News of the Week – June 23, 2024 (CLICK TO VIEW)
- Phase 3 study (IMROZ) results of isatuximab, bortezomib, lenalidomide, and dexamethasone (Isa-VRD) versus VRD for transplant-ineligible patients with newly diagnosed multiple myeloma (NDMM)
- Glofitamab (CD20:CD3 bispecific antibody) plus gemcitabine and oxaliplatin (Glofit-GemOx) versus Rituximab(R)-GemOx for Relapsed/Refractory (R/R) Difusse Large B-Cell Lymphoma (DLBCL): results of a global randomized phase III trial (STARGLO)
- First results of the APOLLO trial: a randomized phase III study to compare arsenic trioxide (ATO) plus all-trans retinoic acid (ATRA [arm A]) versus standard ATRA plus Idarubicin (AIDA regimen [arm B]) for patients with newly diagnosed, high-risk acute promyelocytic leukemia (HR-APL)
- ENERGIZE: a global phase 3 double-blind, randomized, placebo-controlled study of mitapivat demonstrating efficacy and safety in adults with alpha- or beta-non-transfusion-dependent thalassemia (α- or β-NTDT)
- Asciminib (ASC) provides superior efficacy and excellent safety and tolerability versus tyrosine kinase inhibitors (TKI) in newly diagnosed chronic myeloid leukemia (ND-CML) in the pivotal ASC4FIRST study
- The landscape of TP53 mutations and their prognostic impact in Chronic Lymphocytic Leukemia (CLL)
- Acalabrutinib (acala) plus bendamustine and rituximab (BR) in untreated mantle cell lymphoma (MCL): results from the phase 3, double-blind, placebo-controlled ECHO trial
- Guidelines session: EHA-ESMO Clinical Practice Guideline on primary central nervous system lymphoma (PCNSL)
News of the Month – June 7, 2024 (CLICK TO VIEW)
- Abstract number: e1901. Evolving patterns of transplant strategies for mantle cell lymphoma in the era of BTK inhibitors and CAR-T therapy
- Abstract number: 7073. Survival outcomes after autologous stem cell transplantation in T follicular helper type lymphoma
- Abstract number: e19043. Survival benefit of autologous transplant (ASCT) for mantle cell lymphoma (MCL) in the California Cancer Registry (CCR)
- Abstract number: e1903. Relapsed Hodgkin lymphoma autologous stem cell transplant long term follow up
- Abstract number: 7032. Epcoritamab + R-DHAX/C in transplant-eligible patients (pts) with high-risk relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL)
- Donor lymphocyte infusion (DLI) after allogeneic hematopoietic cell transplantation (allo-HCT) for hematological malignancies.
- From 50th Annual Meeting of the EBMT
- Fecal microbiota transplantation for high-risk treatment-naïve acute graft-versus-host disease (GVHD)
- Peripheral blood (PB) stem cell versus bone marrow (BM) graft in reduced intensity conditioning (RIC) haploidentical hematopoietic stem cell transplantation (Haplo-SCT) for acute myeloid leukemia (AML) in complete remission (CR)
- Improved outcome of allogeneic transplantation (AlloSCT) in older patients treated for myeloid malignancies using post-transplantation cyclophosphamide (PTCy) and reduced duration of immune suppression
- Efficacy of autologous (AutoSCT) and allogeneic hematopoietic cell transplantation (AlloSCT) in adults with acute promyelocytic leukemia (APL)
News of the Week – June 2, 2024 (CLICK TO VIEW)
- Oral azacitidine in patients with relapsed or refractory follicular helper T-cell lymphoma
- Risk stratification in Waldenström macroglobulinemia
- VEXAS syndrome and thrombosis
- Tattoos as a risk factor for malignant lymphoma
- Consensus guidelines and recommendations for the management and response assessment of chimeric antigen receptor (CAR)-T cell therapy in clinical practice for relapsed and refractory multiple myeloma
News of the Week – May 26, 2024 (CLICK TO VIEW)
- Monoclonal Gammopathy of Undetermined Significance
- Multiple myeloma and minimal residual disease
- Multiple myeloma and chimeric antigen receptor-T cell therapy
- Relapsed/refractory large B‐cell lymphoma
News of the Week – May 19, 2024 (CLICK TO VIEW)
- Mature T- and NK-cell neoplasms
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
News of the Week – May 12, 2024 (CLICK TO VIEW)
- Measurable residual disease in multiple myeloma
- “Minimal” residual disease in multiple myeloma
- Untreated mantle cell lymphoma
- Immune thrombotic thrombocytopenia purpura treatment
- Relapsed or refractory primary mediastinal large B-cell lymphoma
- Relapsed or refractory marginal zone lymphoma
News of the Week – May 5, 2024 (CLICK TO VIEW)
- Chimeric antigen receptor (CAR) T-cells, bispecific antibodies (BsAbs), and relapsed and refractory large B-cell lymphoma (R/R LBCL)
- Chimeric antigen receptor (CAR) T-cells and Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL)
- Myelodysplastic syndromes (MDS)
- Acute myeloid leukemia (AML)
- Monoclonal B-cell lymphocytosis (MBL)
News of the Week – April 28, 2024 (CLICK TO VIEW)
- Hemoglobinopathies & gene edition
- Chimeric antigen receptor T cell (CAR T) therapy and allogeneic hematopoietic stem cell transplantation (allo-HSCT)
- Primary sinonasal diffuse large B-cell lymphoma (PSDLBCL)
- Polycythemia vera (PV)
- Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) syndrome
- Post-transplant lymphoproliferative disorder (PTLPD)
News of the Week – April 21, 2024 (CLICK TO VIEW)
- Chronic graft-vs-host disease (cGVHD)
- Immune effector cell therapy-associated cytokine release syndrome
- Multiple myeloma (MM) and chimeric antigen receptor T (CAR T) cell therapy
- Non-Hodgkin lymphoma (NHL) and bispecific antibodies (BsAb)
- Diffuse large B-cell lymphoma (DLBCL)
News of the Week – April 14, 2024 (CLICK TO VIEW)
- Acute myeloid leukemia (AML)
- Infections in secondary hypogammaglobulinemia in hematological malignancies.
- Relapsed/refractory multiple myeloma (RRMM)
- Cardiotoxicity and non-Hodgkin lymphoma (NHL)
- Triple negative-primary myelofibrosis (TN-PMF)
- Mature T-cell lymphomas (TCL) and chimeric antigen receptor T (CAR T) therapies
News of the Week – April 7, 2024 (CLICK TO VIEW)
- AL amyloidosis
- Monoclonal gammopathy of undetermined significance (MGUS)
- Extranodal natural killer/T cell lymphoma (ENKTL)
- Chimeric antigen receptor T (CAR T) therapies
- Acute myeloid leukemia (AML)
News of the Week – March 31, 2024 (CLICK TO VIEW)
- Primary immune thrombocytopenia (ITP) therapies
- Primary testicular lymphoma (pTL)
- Hemophilia B
- Paroxysmal nocturnal hemoglobinuria (PNH)
- Multiple myeloma (MM)
- Hematopoietic cell transplantation (HCT) and cellular therapies.
News of the Week – March 24, 2024 (CLICK TO VIEW)
- Chimeric antigen receptor T cell (CAR-T) therapies
- Acute myeloid leukemia (AML)
- B-cell malignancies
- Central nervous system (CNS) B-cell lymphoma
- Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)
- Myelofibrosis
News of the Week – March 17, 2024 (CLICK TO VIEW)
- Paroxysmal nocturnal hemoglobinuria (PNH)
- Acute myeloid leukemia (AML)
- Chronic myeloid leukemia (CML)
- Autoimmune hemolytic anemia (AIHA)
News of the Week – March 10, 2024 (CLICK TO VIEW)
- Multiple myeloma (MM) – DREAMM-8 phase III trial (NCT04484623)
- T-prolymphocytic leukemia (T-PLL) – phase II study (NCT03873493)
- High-risk myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) – safety and efficacy of prophylactic maintenance therapy with venetoclax and azacitidine
- Aplastic anemia (AA) – SOAR (NCT02998645)
- Chimeric antigen receptor (CAR)-T-cell therapy – Rare secondary T-cell lymphomas after CD19- and BCMA-directed CAR-T-cell therapy