IACH News of the week
IACH News of the Week, curated by Dr Edwin Uriel Suárez , is a weekly summary of the latest advancements and discoveries in the field of hematology compiled in an easy-to-digest format. It highlights research breakthroughs, clinical trial results, interesting case studies, and important health advisories – all within the last week. This is a valuable tool for medical professionals with limited time to stay up-to-date on the ever-evolving world of hematology.
- IFM 2026 Recommendations for First-Line Treatment of Newly Diagnosed Multiple Myeloma
- High time for risk-adapted treatment in mantle cell lymphoma (Review)
- High-dose chemotherapy followed by autologous stem-cell transplantation versus non-myeloablative consolidation in primary CNS lymphoma (MATRix/IELSG43): a randomised phase 3 trial
- Blinatumomab for Replacing Chemotherapy in Pediatric Acute Lymphoblastic Leukemia (Phase 3 Clinical Trial)
- Myelodysplasia in VEXAS syndrome (Review)
- American Society of Hematology 2026 guidelines for the diagnosis and management of severe and very severe acquired aplastic anemia
- How I Treat Pediatric Hematology-Oncology Patients from Families Identifying as Jehovah’s Witnesses (Review)
- Outbreak of Severe Methemoglobinemia during Maritime Migration (Descriptive case series)
- Diagnostic Accuracy of Fat Pad Sampling and Bone Marrow Biopsy for AL Amyloidosis: A Systematic Review and Meta-Analysis
- Low-dose ruxolitinib for graft-versus-host disease prevention in haploidentical haematopoietic stem-cell transplantation: a multicentre, open-label, randomised, controlled, phase 3 trial
- Abnormal serum immunofixation patterns are common after BCMA CAR-T in multiple myeloma and are preceded by immune events (Retrospective study)
- Arlocabtagene autoleucel: a GPRC5D-targeted CAR T-cell therapy for heavily pretreated relapsed/refractory multiple myeloma (Phase 1 clinical trial)
- Frequency, kinetics, and clinical significance of HHV-6 DNAemia after PTCy-based hematopoietic cell transplant (Prospective cohort study)
- Consolidation Therapy with Checkpoint Inhibitors After Autologous Hematopoietic Cell Transplantation in Patients with High-Risk Multiple Myeloma and Lymphoma (Prospective study)
- PTCy-based allo-BMT platform as a curative, accessible alternative for pediatric and young adult severe aplastic anemia (Retrospective cohort)
- TA-TMA and GVHD are distinct consequences of endothelial injury: a MIDAS consortium study [Prospective cohort]
- Older Age, STAG2, and DNMT3A Mutations Predict Superior Posttransplant Survival in Newly Diagnosed Acute Myeloid Leukemia Treated With Venetoclax Plus Hypomethylating Agents (Retrospective cohort)
- Mitigating HLA Disparity in AML Transplantation: Comparable Outcomes After Haploidentical and 9/10 Mismatched Unrelated Donor Transplantation With Treosulfan and PTCy (Retrospective cohort)
- Outcomes After Matched Sibling Donor Versus Haploidentical Hematopoietic Stem Cell Transplantation With Post-Transplant Cyclophosphamide-Based GVHD Prophylaxis (Retrospective cohort)
- Azacitidine–Venetoclax or Induction Chemotherapy for Acute Myeloid Leukemia (Phase 2 clinical trial)
- Early treatment with rasburicase and risk of kidney replacement therapy and death in adults with tumour lysis syndrome: emulated target trial
- A framework to challenge the dogma of incurability in follicular lymphoma (Review)
- Technical Considerations in the choice and use of ctDNA for Large B-cell lymphoma (LBCL) (Review)
- New Paradigms in the Management of Castleman Disease (Review)
- Multiple Myeloma: 2026 Update on Diagnosis, Risk-Stratification and Management (Review - ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES from American Journal of Hematology).
- Redefining plasma cell leukaemia (Personal View from The Lancet Haematology journal)
- How I prevent infections in adults receiving bispecific antibody therapies for advanced B-cell malignancies (Review - How I Treat from Blood journal)
- American Society of Hematology 2026 Guidelines for Immune Thrombocytopenia (ITP): Initial and Second-Line Therapy in Adults with Primary ITP
- Guideline on the emergency management of critical bleeding in patients with immune thrombocytopenia
- Avatrombopag Versus Placebo for Persistent Chemotherapy-Induced Thrombocytopenia in GI Cancers: The Phase II ACT-GI Trial
- The diagnosis and management of primary mediastinal B-cell lymphoma: A British Society for Haematology guideline
- Eltrombopag plus cyclosporine A for moderate aplastic anemia (EMAA): a placebo-controlled, double-blind, phase 3 trial
- Myeloproliferative Neoplasms (Review Article)
- Continuous or Fixed-Duration Maintenance Therapy in Multiple Myeloma (Phase 3 clinical trial)
- YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With Cancer. A Randomized Clinical Trial
- Polatuzumab Vedotin Plus Rituximab, Gemcitabine, and Oxaliplatin in Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Results From the Phase III, Randomized POLARGO Trial
- Update of the decision-making algorithm on selecting transfusion-dependent β-thalassemic patients for gene therapy approaches: joint consensus report on behalf of EHA-specialized working group and EBMT hemoglobinopathies working party
Looking for earlier issues? Visit the News of the Week Archive.